Bell's theorem states that any physical theory that incorporates local realism and the no-conspiracy assumption cannot reproduce all the predictions of quantum mechanical theory.
Hence, we cannot develop a theory of local hidden variables if we assume non-conspiracy.
If we assume the freedom of choice of the experimenter (to, for example, measure the x-axis rather than the y-axis in an experiment), how do we maintain determinism in, for example, the MWI? Doesn't the very fact that she has freedom to choose necessitate that her actions are not physically determined?