For various reasons, experts, since Dirac, believe that a unified field theory must have a magnetic monopole. For example, Polyakov said: "I am quite certain that magnetic monopoles really exist. How, when and if they will be found is another matter."
Strangely, thinking that so many elementary particles in the Standard Model, we don't have any particle carry any U(1) magnetic monopole charge --- which should exist for a compact Abelian U(1) gauge theory. For examples, quarks and leptons, they can carry various charges of the electric U(1)$_{em}$ and the weak charge SU(2)$_{weak}$; and the quarks also carry the strong charge, the SU(3)$_{strong}$ colors. Again, we still don't have any elementary particles carrying the U(1) magnetic monopole charge.
For a theoretical purpose, is it possible to have an elementary particle like quarks and leptons in the Standard Model attached a U(1) magnetic monopole?
If yes, how could we make the Standard Model becomes consistent under the U(1) magnetic monopole attached to some known quarks or leptons?
If no, is that the no-go reason due to (1) the fact of the gauge-gravity anomaly-cancelation in Standard model, such as a simple version of the Green–Schwarz mechanism for the Standard model? Or, is the no-go that due to the fact that the U(1) magnetic monopole is actually a topological charge, so it cannot be locally gauge-invariant, and it can not be created by a local operator? Or something else?
The known anomaly cancellation for the Standard model is described in Peskin and Schroeder Chap 20.2: