In quantum electrodynamics (QED), for example, we can calculate any scattering amplitude using the Feynman diagram perturbative expansion. That is, we can calculate the matrix element $\langle i | f \rangle$, where $|i\rangle$ represents some collection of particles coming in from $t = -\infty$ with specified momenta, and $|f\rangle$ represents some collection of particles going out to $t = +\infty$ with specified momenta.
In contrast, the derivation of the Lamb shift appears somewhat ad hoc: it does not seem to be an instance of a general technique, nor does it suggest any general approach to computing properties of bound states in QED. The derivation of the Casimir effect also seems ad hoc.
In non-relativistic quantum mechanics, one writes down the Schrödinger equation and then solves it, and the wave function tells you everything you need to know about the system. Does there exist a general technique in quantum field theory (QFT) for calculating anything other than scattering amplitudes?