I am thinking of this possible answer motivated by the comments of Solenodon Paradoxus.
Solenodon had mentioned that locally its possible to diagonalize the metric. I am wondering if this can be generalized, leading to an interpretation of the off-diagonal elements.
Since, the metric is a symmetric square matrix, it should be always be possible to diagonalize it (even globally) by determining the eigenvalues and eigenvectors. Let $\Lambda$ be the eigenvalue diagonal matrix and $V$ be the eigenvector matrix. Then
$g_{\mu\nu} = V^{\dagger}\Lambda V$,
where, V and $\Lambda$ may in general be complicated non-linear functions of $x$ and $t$ (depending upon the original metric $g_{\mu\nu}$).
Now, the above can be interpreted as $\Lambda$ being the diagonal metric tensor of the modified coordinate system where
$\begin{bmatrix} dt'\\dx' \end{bmatrix} = [V] \begin{bmatrix} dt\\dx \end{bmatrix}$
Since $V$ can be any function of $x$ and $t$, $dx'$ and $dt'$ and hence, $x'$ and $t'$ can also be in general non-linear functions of $t$ and $x$. i.e. $t' = f(x,t)$ and $x' = h(x,t)$.
${\bf Interpretion~ of~ the~ non-diagonal~elements~of~the~metric~tensor~g_{\mu\nu}}$:
We now come to the interpretation part.
$x' = h(x,t)$, means that the co-ordinate axis $x'$ is moving/changing with time $t$. The co-ordinate axis are dynamic. A person sitting in a car at point $x'$ with his engine off, would still be moving w.r.t. and observer at infinity, based on the $t$ dependence of $x'$.
If however, $g_{xt}$ were to be zero, $x'$ would not be a function of time $t$. Meaning if $g_{xt}$ were zero, $x'$ would be curved but stationary/static.
Thus $g_{xt}$ leads to a co-ordinate axis which is changing dynamically.
Please let me know if anyone sees an issue with this solution, of if this solution is incorrect.