It first needs to be clear what you understand by "artificially" and "naturally". The LCH (as well as others particles accelerators) creates the conditions to produce particles (and antiparticles) by collisions of high-energy particles. Is that artificial or natural? In theoretical physics, is not common to think with those categories. At the end, you're always finding a description of all possible processes you can find in nature (or reproduce in the laboratory). If you are thinking about "manipulating" a quantum field or something like that, then no, at least in my opinion. Quantum fields are, in the end, theoretical descriptions that humans have created. In the actual theory, they don't have a direct physical realism, like the energy (or, in general, the observables), but are part of a mathematical structure. In some QFT descriptions, they are operators, in others, distributions, in others, local excitations, etc. They just allow you to understand those processes related to particles creation/annihilation. If by artificial you mean to artificially array some conditions to produce particles, then yes, and that's actually what is made in particles accelerators. But in that way of thinking, all laboratory conditions are artificials (which is not actually wrong but not also opposed to nature).