According to answers to "What is the temperature of an atomic nucleus?" the temperature inside a nucleus is in the thermal equilibrium with outside environment.
So for an outside temperature of 10^N, for N=2 the effect is virtually zero, but at N=12 the nucleons will be turned into Quark-Gluon plasma. At some smaller N, I suppose, the nucleons will be intact but the nucleus will be unbound (turned into baryon plasma/hydrogens?).
What is the N (and therefore temperature) that would noticeably affect the nucleus, such as decreasing the half-life of Radium nucleus by one second?