Some things were already mentioned in the comments but I figured a recap might not hurt.
So generally the answer depends on a lot of factors. Some of which I will discuss in the following.
The first information one needs to settle on in the manifold $M$ on which you want your physics to happen, together with the metric on that manifold. Now for your case, this will likely be $\mathbb{R}^{d,1}$, i.e. Minkowski space. However, note that generally, this may differ e.g. if you are looking to couple your theory to gravity the metric will be determined dynamically.
I will assume $\mathbb{R}^{d,1}$ from now on.
The next parameter to fix is probably going to be the fields you want to couple (here the real scalar $\phi$ ) which will determine the particle content of your final theory.
Now there are (as far as I can see) two more things to determine: The first is the global symmetry group (or the introduction of gauge symmetries) your theory should contain.
Lorentz invariance should almost always be contained in your choice of the symmetry group, however otherwise this really depends on your physics. E.g. for a lot of systems, a $\mathbb{Z}_2$ symmetry or $O(n)$ symmetry is introduced.
Now the next step is to write down all terms you can build from your fields and (appropriate) derivatives thereof that are compatible with your symmetry group.
E.g. for your theory, this would be all terms of the form $\prod_{i} \partial_\mu^{n_i} \phi^{m_i}$, where all partial derivatives have to be contracted in order for the theory to be Lorentz invariant. The Lagrangian would then be any arbitrary sum of these terms. (I think this is all of them at least but sometimes in more complicated theories there are non-obvious topological terms or the like that are easy to miss).
Now the last thing you have to think about is kind of subtle. This has to do with the renormalization of your theory, something I am not sure you have learned about yet. The essence of this idea is that your low-energy physics should not depend on the high-energy details of your lagrangian, though the way to see what effect this actually has is a little complicated so I'm not going to explain it here.
The essence however is that your terms will split into two subsets:
Renormalizable and non-renormalizable terms.
The effect of this depends on the situation. Certain theories one only thinks of being valid at certain energies, these are called effective field theories and here you can just ignore the renormalizability of your terms and essentially freely pick which terms your lagrangian includes. (e.g. just compare with experiment which terms give the best scattering amplitudes).
If your theory however should be viewed as a true high-energy description of your physics you have to exclude all non-renormalizable terms from your Lagrangian. Which terms these correspond to depends on the dimension of your Manifold and the exact choices of fields as this has to do with the energy/mass dimension of terms e.g. $[\phi] = (d-1)/2$ and $[\partial] = 1$ allows you to calculate the mass dimension of $\partial^n \phi^m$ terms. Only terms with dimensions smaller than $-[d^{d+1}x]$ should be included. Which reduces the number of allowed terms considerably. (This is e.g. the reason why higher derivative terms do not show up in $3+1 d$ for your theory)
As such the question if your Lagrangian is the most general depends on the dimension and symmetry group, as well as its application.