I'm coming at the following question from a mostly lay perspective (i.e. barely-undergrad physics), so please bear with the weirdness of it if possible.
I've generally been uncomfortable with the feeling that the -1 (i.e. $-+++$ or $+---$) is mathematically arbitrary because it fits the data, i.e. there's no mathematical reason there "should" be a sign flip (at least no obvious one to me). But I remembered a bit about path-ordering and was thinking that time is somehow different because there's a time-ordering operator which must be imposed on quantum evolution operators due to non-commutativity. Is there any evidence that this would have any link to the sign flip in relativity?
(of course any physical theory could be described as "mathematically arbitrary/just fits the data", but would be nice to have less axioms)
Edit (based on comment): The question is does the non-triviality of the time-ordering (which I would interpret as a kind of 'casual behavior') have any connection with the fact that timelike dimensions have the opposite sign of spacelike ones in Minkowski space?